STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94108.1The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Signal peptide of lipoprotein cleaved between the residues 24 and 25; Possibly localized in the outer membrane; Function unclear. (266 aa)    
Predicted Functional Partners:
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
  
 
 0.853
CAZ94109.1
Conserved hypothetical membrane protein; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
   0.785
CAZ94110.1
Conserved hypothetical protein featuring a C-terminal helix-turn-helix DNA-binding motif. Localized in the cytoplasm; Conserved hypothetical protein.
       0.773
CAZ94111.1
Conserved hypothetical membrane protein; Could belong to the Isoprenylcysteine carboxyl methyltransferase (ICMT) family; Contains three transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
       0.557
CAZ97308.1
The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear.
  
     0.549
serB/serA1
Phosphoserine phosphatase / D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.535
lipA
Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity.
  
     0.436
CAZ94868.1
The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear.
  
     0.431
rdgB
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
 
 0.428
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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