STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97639.1ROK-type transcriptional repressors are involved in the repression of genes encoding for sugars-utilizing enzymes and are important in the coordination of catabolic and transport operons; Contains a N-terminal helix-turn-helix (HTH) DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA; Belongs to the ROK (nagC/xylR) family; Localized in the cytoplasm; Family membership. (411 aa)    
Predicted Functional Partners:
CAZ97642.1
Large protein containing a central carbohydrate binding module of the family 35 (CBM35) and at least two other domains of unknown function; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership.
 
   
 0.741
CAZ97640.1
Sulfatase, family S1-17; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Family membership.
  
    0.607
CAZ97638.1
Hypothetical protein; Localized in the cytoplasm.
       0.561
CAZ97641.1
Sulfatase, family S1-25; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 25; Lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership.
  
    0.529
CAZ97662.1
Modular protein with a N-terminal acetylesterase (lipase-GDSL family), which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12), a central alpha/beta hydrolase fold domain and a C-terminal GDSL_hydrolase fold domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Specificity unclear.
 
     0.501
CAZ97644.1
Carbohydrate esterase, family CE6; Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad; Belongs to the family 6 of the carbohydrate esterases CE6); Localized in the cytoplasm; Specificity unclear.
 
     0.495
CAZ97646.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership.
 
     0.434
phoD1
Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Localized in the cytoplasm; High confidence in function and specificity.
  
     0.433
CAZ97645.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (30-103) and the Plug module (119-227) acting as a channel gate; The signal peptide is cleaved between the residues 29 and 30; Family membership.
 
     0.428
CAZ97677.1
Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership.
  
     0.403
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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