STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97654.1Endo-1,4-beta-xylanase, family GH5; Endo-1,4-beta-xylanase catalyzes the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. This enzyme belongs to the family 5 of the glycoside hydrolases. Features a signal peptide cleaved between residues 19 and 20. Localized in the periplasm; High confidence in function and specificity. (512 aa)    
Predicted Functional Partners:
CAZ97655.1
Sulfatase, family S1-20; Modular protein consisting of a N-terminal domain belonging to the family 1 of sulfatases and a C-terminal PA14 domain putatively involved in the protein or carbohydrate binding; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; localized [...]
 
  
 0.784
CAZ97653.1
Sulfatase, family S1-20; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Family membership.
 
  
 0.692
xylB
Beta-xylosidase, family GH43; Enzyme that hydrolyzes the beta-1,4-D-xylans linkage, to remove successive D-xylose residues from the non-reducing termini; Belongs to the family 43 of the glycoside hydrolase (GH43); Protein localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.641
xynB
Beta-xylosidase, family GH43; Beta-xylosidase is an intracellular xylan-degrading enzyme. It catalyzes the hydrolysis of 1,4-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini. It belongs to the family GH43 of the glycoside hydrolases; High confidence in function and specificity.
  
 
 0.578
xarB2
Xylosidase/arabinosidase, family GH3; XarB catalyzes the hydrolysis of terminal, non-reducing beta-D-xylose residues (or L-arabinose residues) with release of beta-D-xylose (or alpha-L-arabinose). This bifunctional enzyme belongs to the family 3 of the glycoside hydrolases. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane; High confidence in function and specificity.
    
 0.535
CAZ97652.1
Protein that consists of a GDSL-like Lipase/Acylhydrolase domain; Seems to have an uncleavable N-terminal signal sequence; Possibly localized in the cytoplasmic membrane; Family membership.
 
   
 0.520
CAZ97648.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
     0.515
CAZ97650.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Probably localized in the outer membrane; Family membership.
 
     0.501
CAZ97649.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly sulphated sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; This sequence does not contain of carboxypeptidase regulatory domain. The Plug module (111- 221) acts as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership.
 
     0.490
CAZ94287.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-99) and the Plug module (115-223) acting as a channel gate; The signal peptide is cleaved between the residues 17 and 18; Family membership.
  
     0.449
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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