STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
rhaAAlpha-L-rhamnosidase, family GH78; Alpha-L-rhamnosidase catalyzes the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides. It belongs to the family 78 of the glycoside hydrolases. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane; High confidence in function and specificity. (846 aa)    
Predicted Functional Partners:
CAZ97661.1
This enzyme is a modular protein consisting of a N-terminal module belonging to the family 6 of the carbohydrate esterases (CE6; 26-342), a central alpha-galactosidase domain belonging to family 27 of the glycoside hydrolases (GH27; 343-733) and a C-terminal domain of unknown function (734-866). Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad. Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharide [...]
     0.742
CAZ97662.1
Modular protein with a N-terminal acetylesterase (lipase-GDSL family), which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12), a central alpha/beta hydrolase fold domain and a C-terminal GDSL_hydrolase fold domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Specificity unclear.
 
     0.719
CAZ97642.1
Large protein containing a central carbohydrate binding module of the family 35 (CBM35) and at least two other domains of unknown function; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership.
  
     0.619
alfA4
Alpha-L-fucosidase, family GH29; Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 27 and 28; Localized in the periplasmic space; High confidence in function and specificity.
  
     0.610
CAZ98075.1
Conserved protein belonging to the DUF1680 family protein. Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Family membership.
 
    0.577
CAZ97301.1
Conserved hypothetical oxydoreductase; Contains an hypothetical N-terminal aldolase II domain and a C-terminal domain belonging to the short chain dehydrogenase family; Localized in the cytoplasm; Specificity unclear.
 
   0.568
CAZ97663.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership.
 
     0.554
CAZ97657.1
Sulfatase, family S1-27; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 27; Possible lipoprotein signal peptide cleaved between the residues 27 and 28; Putatively localized in the outer membrane; Family membership.
 
     0.550
alfA5
Alpha-L-fucosidase, family GH29 / Acetylesterase; Modular protein with a N-terminal alpha-L-fucosidase module belonging to the family 29 of the glycoside hydrolases (GH29) and a C-terminal acetyl esterase domain belonging to the lipase-GDSL family which includes families 3 and 12 of the carbohydrate esterases (CE3/CE12); Catalytic activities: an alpha-L-fucoside + H2O = L-fucose + an alcohol and an acetic ester + H2O = an alcohol + acetate; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear.
  
     0.513
bgaE
Beta-galactosidase, family GH2; Modular protein with a N-terminal beta-galactosidase domain belonging to the family 2 of glycoside hydrolases (GH2, TIM alpha/beta barrel fold) and a C-terminal Carbohydrate Binding Module of family CBM35; Catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing, releasing a beta-D-galactose residue from beta-D-galactosides; Signal peptide cleaved between residues 28 and 29; Localized in the periplasmic space; High confidence in function and specificity.
 
   0.511
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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