STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97661.1This enzyme is a modular protein consisting of a N-terminal module belonging to the family 6 of the carbohydrate esterases (CE6; 26-342), a central alpha-galactosidase domain belonging to family 27 of the glycoside hydrolases (GH27; 343-733) and a C-terminal domain of unknown function (734-866). Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad. Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharide [...] (866 aa)    
Predicted Functional Partners:
nanH
Sialidase, family GH33; Sialidase catalyzes the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. It belongs to the family 33 of the glycoside hydrolases. Features a signal peptide cleaved between residues 26 and 27. Localized in the periplasm; High confidence in function and specificity.
  
  
  0.914
CAZ94389.1
Alpha-glucosidase, family GH97; Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic or outer membrane or both; High confidence in function and specificity.
  
  
  0.913
CAZ94428.1
Alpha-glucosidase, family GH97; Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; High confidence in function and specificity.
  
  
  0.911
CAZ97662.1
Modular protein with a N-terminal acetylesterase (lipase-GDSL family), which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12), a central alpha/beta hydrolase fold domain and a C-terminal GDSL_hydrolase fold domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Specificity unclear.
 
     0.910
malL
Oligo-1,6-glucosidase, family GH13; Oligo-1,6-glucosidase catalyzes the hydrolysis of 1, 6-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose; Belongs to the family 13 of the glycoside hydrolases; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.910
malA
Alpha-glucosidase, family GH31; Alpha-glucosidase catalyzes the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. It belongs to the family 31 of the glycoside hydrolases. Involved in starch or glycogen metabolism; High confidence in function and specificity.
    
 0.905
mroA2
Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Localized in the cytoplasm; High confidence in function and specificity.
  
 
  0.903
mroA1
Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; localized in the cytoplasm; High confidence in function and specificity.
  
 
  0.903
mroA3
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
  0.903
mroA4
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
  0.903
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.