STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97677.1Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership. (320 aa)    
Predicted Functional Partners:
CAZ97675.1
Sulfatases, family S1-23; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Signal peptide of lipoprotein cleaved between the residues 22 and 23, Localized in the outer membrane; Family membership.
 
    0.819
phoD1
Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.779
CAZ97676.1
Sodium/substrate symporter actively transports glucose into cells by Na+ cotransport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.773
CAZ95842.1
Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 1 family; Localized in the cytoplasm; Family membership.
 
 
 0.687
afcA6
Alpha-L-fucosidase, family GH95; The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Signal peptide cleaved between residues 25 and 26; Localized in the periplasmic space; High confidence in function and specificity.
 
    0.638
CAZ97644.1
Carbohydrate esterase, family CE6; Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad; Belongs to the family 6 of the carbohydrate esterases CE6); Localized in the cytoplasm; Specificity unclear.
 
  
 0.622
CAZ97642.1
Large protein containing a central carbohydrate binding module of the family 35 (CBM35) and at least two other domains of unknown function; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership.
  
     0.556
CAZ97679.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership.
 
     0.512
CAZ97661.1
This enzyme is a modular protein consisting of a N-terminal module belonging to the family 6 of the carbohydrate esterases (CE6; 26-342), a central alpha-galactosidase domain belonging to family 27 of the glycoside hydrolases (GH27; 343-733) and a C-terminal domain of unknown function (734-866). Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad. Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharide [...]
  
     0.486
CAZ95096.1
Dioxygenase, PhyH family; Dioxygenase catalyzes the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate. The exact specificity of this enzyme is unknown; Belongs to the phytanoyl-CoA dioxygenase (PhyH) family; Localized in the cytoplasm; Family membership.
  
     0.482
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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