STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97690.1Two-component system-Response regulator, receiver domain; The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership. (145 aa)    
Predicted Functional Partners:
CAZ97126.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains three N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership.
 
  
 0.782
CAZ98039.1
The sensor histidine kinase belongs to two-component signal transduction systems. It autophosphorylates an histidine in its phosphoacceptor domain and phosphorylates an aspartic acid present in the response regulator receiver domain; Contains a CheB-type methylesterase catalytic domain and a CheR-type methyltransferase domain, both involved in the bacterial chemotaxis system; Contains a PAS/PAC domain; Seems localized in the cytoplasm; Family membership.
 
   
 0.772
CAZ95146.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and two N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Localized in the cytoplasmic membrane; Family membership.
 
   
 0.765
CAZ97057.1
Two-component system-Response regulator, receiver domain; The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership.
 
 
 0.733
CAZ96721.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership.
 
 
 
 0.724
CAZ97056.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership.
 
     0.706
CAZ97128.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Possibly localized in the cytoplasm; Family membership.
 
     0.698
CAZ95484.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains three N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Putatively localized in the cytoplasm; Family membership.
 
 
 
 0.667
CAZ94751.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains one N-terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership.
 
 
 
 0.656
CAZ94142.1
The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain and of the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain. A transmembrane segment separates this part from the periplasmic part that contains three tetratrico peptide repeats; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.599
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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