STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97722.1The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership. (861 aa)    
Predicted Functional Partners:
CAZ94142.1
The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain and of the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain. A transmembrane segment separates this part from the periplasmic part that contains three tetratrico peptide repeats; Localized in the cytoplasmic membrane; Family membership.
 
 0.946
CAZ94242.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.934
CAZ94779.1
The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain and of the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain. A transmembrane segment separates this part from the periplasmic part that contains three tetratrico peptide repeats; Localized in the cytoplasmic membrane; Family membership.
 
0.933
CAZ98300.1
Two-component system-Response regulator, receiver domain; The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership.
 
 
 0.931
CAZ97721.1
Two-component system-Response regulator, receiver domain; The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership.
 
 
 
 0.930
CAZ97648.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.929
CAZ98754.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.929
CAZ96458.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.926
CAZ94252.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains a transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.925
CAZ94288.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.922
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.