STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94432.1RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership. (192 aa)    
Predicted Functional Partners:
CAZ94431.1
Anti-sigma factor; This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership.
 
   0.798
CAZ94433.1
Conserved hypothetical protein; Contains four tetratrico peptide repeats (TPRs). The TPR motif consists of 316 tandem-repeats of 34 amino acids residues. It adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. TPRs mediate proteinprotein interactions; Localized in the cytoplasm.
  
    0.777
CAZ97194.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
  
     0.760
CAZ98070.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
  
     0.735
CAZ98082.1
Anti-sigma factor; This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership.
  
   0.680
CAZ94434.1
Putative protein.
       0.664
CAZ97667.1
Anti-sigma factor; This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership.
  
   0.601
CAZ94776.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
  
     0.599
CAZ98256.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
  
     0.581
CAZ94961.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
  
     0.569
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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