STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97781.1Sulfatase, family S1-19; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership. (463 aa)    
Predicted Functional Partners:
CAZ97780.1
Sulfatase, family S1-25; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 25; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Family membership.
 
    
0.762
fucA8
Alpha-L-fucosidase, family GH29; The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 18 and 19; Localized in the periplasmic space; High confidence in function and specificity.
       0.746
CAZ97783.1
Conserved protein belonging to the DUF1080 family. Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space.
  
    0.674
fgeA
C-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear.
 
   0.602
mroA3
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
      0.516
gldK
Lipoprotein involved in the gliding motility that contains an unknown function domain found in some eukaryotic and prokaryotic protein and in eukaryotic proteins required for post-translational modification of sulfatase; Signal peptide cleaved between the residues 17 and 18; Putatively localized in the outer membrane; Function unclear.
 
   0.417
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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