STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
moeA2Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (396 aa)    
Predicted Functional Partners:
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 0.981
CAZ98314.1
Conserved protein; Function unclear.
   
  0.923
moeA1
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
  
 
0.920
moaC
Involved in molybdenum cofactor biosynthesis, MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor Z by inserting the carbon-8 of the purine between the 2' and 3' ribose carbon atoms, which is the first of three phases of molybdenum cofactor biosynthesis; Localized in the cytoplasm; High confidence in function and specificity.
  
 0.917
moaE1
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin in the second major step of the molybdenum cofactor biosynthesis. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.902
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.868
moaE2
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; Hypothetical protein.
 
  
 0.859
moeB
Molybdopterin synthase activating protein; Enzyme involved in the biosynthesis of molybdopterin cofactor, necessary for molybdoenzymes. Plays a role in the activation of the small subunit of the molybdopterin converting factor (moaD); Contains a N- terminal transmembrane segment and a C-terminal rhodanese domain; Belongs to the hesA/moeB/thiF family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 0.733
lepB
Signal peptidase I, family S26; The type-1 signal peptidase (SPase I; also known as leader peptidase I) is a serine protease that removes the signal peptides from the majority of exported pre-proteins. SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by four N-terminal transmembrane segments with the main part of the protein protuding in the periplasmic space; Contains an additional C-terminal transmembrane segments; Belongs to family 26 (clan SF) of serine peptidases (S26), S26A subfamily; High confidence in function and specificity.
       0.680
napA
Periplasmic nitrate reductase, catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 0.634
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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