STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhB3Quinoprotein glucose dehydrogenase; Lipoprotein putatively localized in the outer membrane is a soluble glucose dehydrogenase (s-GDH) that oxidizes glucose to gluconolactone using a quinone as cofactor; Signale peptide cleaved between the residues 18 and 19; Family membership. (373 aa)    
Predicted Functional Partners:
CAZ97863.1
Cytochromes c typically function in electron transfer. The heme group is covalently attached by thioether bonds to two conserved cysteine residues (Cys-x-x-Cys-His motif). The conserved histidine residue is one of the two axial ligands of the heme iron. Features a signal peptide cleaved between the residues 24 and 25. Localized in the periplasm; Specificity unclear.
     0.956
CAZ94658.1
Gluconolactonases hydrolyze the gluconolactone formed by glucose oxidoreductase. The proximity of the galactonate dehydratase gene dgoD suggests that this lactonase would be specific for D-galactono-1,4-lactone instead of gluconolactone; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm; Specificity unclear.
   
 0.535
CAZ97865.1
Conserved hypothetical protein; Signal peptide cleaved between the residues 27 and 28; Putatively localized in the outer membrane (PSORT result).
       0.529
gnlA
Gluconolactonases hydrolyze the gluconolactone, formed either by the glucose oxidoreductase or by the glucose dehydrogenase in aerobic conditions, to gluconate; Contains a putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; High confidence in function and specificity.
   
 0.513
CAZ94391.1
Gluconolactonase or Aldonolactonase hydrolyzes the glyconolactones formed by oxidoreductases acting on various aldohexosaccharides. It hydrolyzes the D-glucono-1,5-lactone to gluconic acid and can act on a wide range of hexono-1,5-lactones; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.508
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.