STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97935.1Conserved protein belonging to a family of putative cyclases. These proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site. Localized in the cytoplasm. (214 aa)    
Predicted Functional Partners:
CAZ97932.1
NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear.
 
     0.872
CAZ97933.1
The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
 
     0.865
CAZ97934.1
Conserved hypothetical protein. Localized in the cytoplasm.
 
   
 0.819
ttuC
Tartrate dehydrogenase/decarboxylase has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. It uses NAD+ as a cofactor. Belongs to the Isocitrate dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.806
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
 0.796
CAZ97937.1
The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership.
 
     0.588
CAZ95617.1
Transcriptional regulator featuring a N-terminal helix-turn-helix DNA binding motif belonging to the Xre family and a C-terminal domain adopting a Cupin barrel fold. Localized in the cytoplasm; Specificity unclear.
  
    0.578
tdoA2
Tryptophan 2,3-dioxygenase is Involved in L-kynurenine metabolism from L-tryptophan,incorporating oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D-and L-tryptophan, 5-hydroxytryptophan and serotonin; This enzyme forms a tetramer and binds 2 hemes per subunit; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.534
tdoA1
Tryptophan 2,3-dioxygenase is Involved in L-kynurenine metabolism from L-tryptophan,incorporating oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D-and L-tryptophan, 5-hydroxytryptophan and serotonin; This enzyme forms a tetramer and binds 2 hemes per subunit; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.534
apbE3
Thiamine biosynthesis protein apbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.451
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.