STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ97940.1Sulfatase, family S1-27; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 27; Lipoprotein with a signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Family membership. (521 aa)    
Predicted Functional Partners:
uglA2
Unsaturated glucuronyl hydrolase, family GH88; Unsaturated glucuronyl hydrolase is involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. UglA catalyzes the hydrolysis of oligosaccharides with unsaturated uronic acids at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated uronic acid, which is nonenzymatically converted immediately to alpha-keto acid; Belongs to the family 88 of the glycoside hydrolases (GH88); Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; Specificity unclear.
     0.794
CAZ97941.1
Beta-helix fold protein; This conserved protein likely adopts a right handed parallel beta-helix fold; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Function unclear.
 
     0.779
sgsA8
The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity.
  
     0.738
CAZ96090.1
Conserved hypothetical protein; Contains a central transmembrane helix; Localized in the cytoplasmic membrane.
  
    0.569
idnO2
Gluconate-5-dehydrogenase; Also called 5-keto-D-gluconate 5-reductase. Catalyzes the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
  
   0.471
CAZ97944.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
       0.468
CAZ97947.1
Conserved hypothetical protein; Localized in the cytoplasm.
      0.426
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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