STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ98177.1TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (32-116) and the Plug module (132-229) acting as a channel gate; The signal peptide is cleaved between the residues 18 and 19; Family membership. (832 aa)    
Predicted Functional Partners:
CAZ98178.1
Conserved hypothetical membrane protein; Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.773
CAZ95933.1
Conserved hypothetical periplasmic protein; Signal peptide cleaved between the residues 19 and 20; localized in the periplasmic space; Conserved hypothetical protein.
  
     0.574
CAZ98195.1
Conserved hypothetical membrane protein; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.532
CAZ94598.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.511
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
     0.481
arsC
Arsenate reductase; ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. Glutaredoxin functions as the electron donor for arsenate reduction. ArsC also uses molybdenum as a cofactor. ArsC expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Localized in the cytoplasm; High confidence in function and specificity.
       0.457
CAZ96441.1
BlaR1-type regulatory proteins are signal-transducing proteins that are a fusion protein with a N-terminal zinc metallopeptidase-M56 domain that proteolytically inactivate the cytoplasmic BlaI-type transcriptional repressor, and a beta-lactams-binding domain; Contains at least four transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear.
  
     0.447
CAZ96991.1
Conserved hypothetical membrane protein; Protein that contains a domain of unknown function DUF1573; Putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Family membership.
  
     0.447
tonB2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   0.441
CAZ94077.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplamic space; Conserved hypothetical protein.
  
 
   0.403
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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