STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ98307.1Peptidase family M14 contains mainly metallocarboxypeptidases. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm; Specificity unclear. (488 aa)    
Predicted Functional Partners:
CAZ98306.1
Amidase catalyzes the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3. The specificity of this enzyme is unknown. Belongs to a protein family including N-acetylmuramoyl-L-alanine amidase. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane; Specificity unclear.
   
 0.961
CAZ98305.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein.
       0.773
gyaR
Glyoxylate reductase converts, in presence of NAD+, the Glycolate into glyoxylate. GyaR is involved in the glyoxylate metabolism (conversion of lipids into glucids); Contains a glycine-rich region located in the central section corresponding to the NAD-binding domain; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity.
       0.661
CAZ97110.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein.
 
     0.648
CAZ98303.1
Protein belonging to the family 12 of Serine peptidases (S12). Could be a beta-lactamase classified as S12 non-peptidase homologues. However, the active site residues Ser and Lys that form the catalytic dyad are found in the motif Ser-Xaa-Thr-Lys; Contains a N-terminal transmembrane segment and a C-terminal beta-lactamase domain; Localized in the cytoplasmic membrane; Function unclear.
       0.473
dacB
D-alanyl-D-alanine carboxypeptidase, also known as Penicillin-binding protein 4, is involved in the peptidoglycan biosynthesis. It hydrolyzes the D-Ala-D-Ala bond in the cross-linking peptide precursor, and performs the transpeptidation reaction between the D-Ala and the meso-2,6-diaminopimelate of adjacent crosslinking peptides of the bacterial cell wall; Belongs to the family S13 of the serine peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 27 and 28; Localized in the outer membrane; High confidence in function and specificity.
  
     0.470
CAZ95746.1
Dipeptidyl peptidase, family C40; Dipeptidyl peptidase hydrolyzes gamma-D-Glu-L-(meso)A2pm linkages only in those peptide units that have a free N-terminal L-alanine. It is involved in peptidoglycan metabolism; Belongs to the family C40 of peptidases; Prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; High confidence in function and specificity.
  
   
 0.438
CAZ95475.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains the Plug module (43-152) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
  
     0.407
CAZ94692.1
Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership.
  
     0.403
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.