Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.

Rieske [2Fe-2S] iron-sulfur protein; Protein that contains an unknown function N-terminal domain and a C-terminal Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines; Prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear.

Enzyme responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Belongs to the pseudouridine synthase RsuA family; localized in the cytoplasm; High confidence in function and specificity.

Conserved protein belonging to the Xylose isomerase-like TIM barrel family; Localized in the cytoplasm; Family membership.

L-sorbosone dehydrogenase converts L-sorbosone into 2-keto-L-gulonic acid (2KGA); Uses one of four different quinone as cofactors for the oxidation of sorbosone; Belongs to the Quinoprotein dehydrogenases family; Lipoprotein with a signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; High confidence in function and specificity.

Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhB is the iron-sulfur subunit. Localized in the cytoplasm; High confidence in function and specificity.

The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity.

Argininosuccinate synthase (AS) is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate; Belongs to the argininosuccinate synthase family, type 1 subfamily; Localized in the cytoplasm; High confidence in function and specificity.

Modular protein with a N-terminal 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) domain and a C-terminal Deoxyguanosine kinase (DGK) domain. HPPK catalyzes the attachment of pyrophosphate to 6-hydroxymethyl-7,8-dihydropterin to form 6-hydroxymethyl- 7, 8-dihydropteridine pyrophosphate. This is the first step in a three-step pathway leading to 7,8 dihydrofolate. Deoxyguanosine kinase DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism. Localized in the cytoplasm; High confidence in function and specificity.