STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ98368.1GAF domain-containing protein; Unnamed protein product; Conserved protein belonging to the GAF family. GAF domains are present in phytochromes and cGMP-specific phosphodiesterases. Localized in the cytoplasm; Family membership. (159 aa)    
Predicted Functional Partners:
CAZ95227.1
Conserved hypothetical protein; Contains a GAF domain; Localized in the cytoplasm.
    
  0.903
metE
5-Methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.900
metH
Methionine synthase, cobalamin-binding module; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.900
metH-2
Methionine synthase, homocysteine-binding module; Methionine synthase or 5-methyltetrahydrofolate-homocysteine S-methyltransferase catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate; L-homocysteine is bound via the zinc atom; Uses the cobalamin (vitamin B12) and zinc as cofactors; This sequence corresponds to the homocysteine-binding domain (Hcy-binding domain) only; Belongs to the vitamin-B12 dependent methionine synthase family; Localize [...]
     
  0.900
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
CAZ98367.1
Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership.
       0.494
CAZ98366.1
NAD(P)H-flavin oxidoreductase; Belongs to the nitroreductase family. This family include the oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) (1.5.1.34) and NADH dehydrogenase (1.6.99.3); Members of this family use FMN as a cofactor; Localized in the cytoplasm; Family membership.
       0.441
CAZ98365.1
Probable NADP-dependent oxidoreductase; Contains an zinc-containing alcohol dehydrogenase superfamily domain; Belongs to the NADP-dependent oxidoreductase L4BD family; Possibly localized in the cytoplasmic membrane or in the cytoplasm; Family membership.
       0.435
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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