STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nfnB2Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity. (219 aa)    
Predicted Functional Partners:
CAZ98366.1
NAD(P)H-flavin oxidoreductase; Belongs to the nitroreductase family. This family include the oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) (1.5.1.34) and NADH dehydrogenase (1.6.99.3); Members of this family use FMN as a cofactor; Localized in the cytoplasm; Family membership.
  
  
 
0.925
nfnB3
Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.921
nfnB1
Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.901
qorA2
The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinones; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
       0.699
CAZ98386.1
Conserved hypothetical protein; Contains a C-terminal Cupin domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space.
       0.604
CAZ98387.1
Conserved hypothetical protein; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space.
       0.604
alkB2
Alpha-ketoglutarate-dependent dioxygenase repairs alkylated DNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Has a strong preference for single-stranded DNA. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Localized in the cytoplasm; High confidence in function and specificity.
       0.445
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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