STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ98482.1TetR-type transcriptional regulator; Contains 1 HTH tetR-type DNA-binding domain (1 to 42) with an helix-turn-helix (HTH) motif (5 to 24); This domain is present in the N-terminal extremity of the tetR family of prokaryotic transcription regulators. The C-terminal part of these regulators contains several regions that can be involved in binding of inducers, which can be antibiotics, antiseptics, disinfectants or host-encoded antimicrobials; Family membership. (204 aa)    
Predicted Functional Partners:
CAZ98481.1
The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Family membership.
 
   
 0.952
ybhG
The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Belongs to the type I secretion system; Specificity unclear.
 
   
 0.949
ybhF2
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership.
 
     0.942
ybhR
ABC-2 type exporter, permease component; ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear.
 
     0.937
ybhS
ABC-2 type exporter, permease component; ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear.
 
     0.930
ybhF1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership.
 
     0.916
CAZ98483.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.400
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.