| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAZ96468.1 | CAZ98502.1 | ZOBELLIA_2313 | ZOBELLIA_4367 | Conserved hypothetical lipoprotein; Contains a signal peptide of lipoprotein cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein. | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | 0.490 |
| CAZ96468.1 | CAZ98503.1 | ZOBELLIA_2313 | ZOBELLIA_4368 | Conserved hypothetical lipoprotein; Contains a signal peptide of lipoprotein cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.408 |
| CAZ96770.1 | CAZ98503.1 | ZOBELLIA_2620 | ZOBELLIA_4368 | SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.412 |
| CAZ98502.1 | CAZ96468.1 | ZOBELLIA_4367 | ZOBELLIA_2313 | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | Conserved hypothetical lipoprotein; Contains a signal peptide of lipoprotein cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein. | 0.490 |
| CAZ98502.1 | CAZ98503.1 | ZOBELLIA_4367 | ZOBELLIA_4368 | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.874 |
| CAZ98502.1 | CAZ98505.1 | ZOBELLIA_4367 | ZOBELLIA_4370 | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm; Function unclear. | 0.580 |
| CAZ98502.1 | folE3 | ZOBELLIA_4367 | ZOBELLIA_4369 | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm; High confidence in function and specificity. | 0.568 |
| CAZ98503.1 | CAZ96468.1 | ZOBELLIA_4368 | ZOBELLIA_2313 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | Conserved hypothetical lipoprotein; Contains a signal peptide of lipoprotein cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein. | 0.408 |
| CAZ98503.1 | CAZ96770.1 | ZOBELLIA_4368 | ZOBELLIA_2620 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership. | 0.412 |
| CAZ98503.1 | CAZ98502.1 | ZOBELLIA_4368 | ZOBELLIA_4367 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | 0.874 |
| CAZ98503.1 | CAZ98505.1 | ZOBELLIA_4368 | ZOBELLIA_4370 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm; Function unclear. | 0.719 |
| CAZ98503.1 | CAZ98507.1 | ZOBELLIA_4368 | ZOBELLIA_4372 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | Hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein. | 0.687 |
| CAZ98503.1 | CAZ98508.1 | ZOBELLIA_4368 | ZOBELLIA_4373 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | ABC transporter, permease component; ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Contains four transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | 0.601 |
| CAZ98503.1 | CAZ98509.1 | ZOBELLIA_4368 | ZOBELLIA_4374 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the ABC transporter permease component; Family membership. | 0.497 |
| CAZ98503.1 | folE3 | ZOBELLIA_4368 | ZOBELLIA_4369 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm; High confidence in function and specificity. | 0.774 |
| CAZ98505.1 | CAZ98502.1 | ZOBELLIA_4370 | ZOBELLIA_4367 | Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm; Function unclear. | Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm; Family membership. | 0.580 |
| CAZ98505.1 | CAZ98503.1 | ZOBELLIA_4370 | ZOBELLIA_4368 | Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm; Function unclear. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.719 |
| CAZ98505.1 | folE3 | ZOBELLIA_4370 | ZOBELLIA_4369 | Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm; Function unclear. | GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm; High confidence in function and specificity. | 0.614 |
| CAZ98507.1 | CAZ98503.1 | ZOBELLIA_4372 | ZOBELLIA_4368 | Hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.687 |
| CAZ98507.1 | CAZ98508.1 | ZOBELLIA_4372 | ZOBELLIA_4373 | Hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein. | ABC transporter, permease component; ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Contains four transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | 0.950 |