STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfnB1Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity. (217 aa)    
Predicted Functional Partners:
CAZ98366.1
NAD(P)H-flavin oxidoreductase; Belongs to the nitroreductase family. This family include the oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) (1.5.1.34) and NADH dehydrogenase (1.6.99.3); Members of this family use FMN as a cofactor; Localized in the cytoplasm; Family membership.
  
  
 
0.926
nfnB3
Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.919
nfnB2
Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.901
lipA
Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity.
  
    0.703
CAZ98611.1
Hypothetical protein. Putatively localized in the cytoplasm.
  
    0.703
CAZ98612.1
Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership.
  
    0.625
pcaC
Modular protein displaying a N-terminal 4-carboxymuconolactone decarboxylase (CMD) domain and a C-terminal conserved domain of unknown function. CMD is involved in protocatechuate catabolism. It converts the 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 4,5-dihydro-5-oxofuran-2-acetate; Localized in the cytoplasm:; High confidence in function and specificity.
  
    0.529
alsD
Alpha-acetolactate decarboxylase converts acetolactate into acetoin, which can be secreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in cytoplasmic and/or the outer membrane; High confidence in function and specificity.
       0.522
qorA1
The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
       0.494
CAZ98608.1
Transcriptional regulator belonging to the HxlR family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm; Specificity unclear.
     
 0.490
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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