STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
qorA1The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity. (312 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein; High confidence in function and specificity.
 
    
 0.901
alsD
Alpha-acetolactate decarboxylase converts acetolactate into acetoin, which can be secreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in cytoplasmic and/or the outer membrane; High confidence in function and specificity.
 
   
 0.855
pcaC
Modular protein displaying a N-terminal 4-carboxymuconolactone decarboxylase (CMD) domain and a C-terminal conserved domain of unknown function. CMD is involved in protocatechuate catabolism. It converts the 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 4,5-dihydro-5-oxofuran-2-acetate; Localized in the cytoplasm:; High confidence in function and specificity.
 
    0.816
CAZ98616.1
Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership.
  
 
 0.748
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
 
 
0.684
lipA
Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity.
 
   0.639
CAZ98617.1
Putative protein.
       0.628
CAZ98612.1
Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership.
  
    0.625
CAZ98618.1
Members of this family are integral membrane proteins that includes the antibiotic resistance protein MarC. These proteins may be transporters; Belongs to the marC (UPF0056) family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership.
       0.588
fabB2
3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.579
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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