| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAZ94457.1 | CAZ98616.1 | ZOBELLIA_384 | ZOBELLIA_4481 | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | 0.548 |
| CAZ94457.1 | fabB2 | ZOBELLIA_384 | ZOBELLIA_1591 | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.927 |
| CAZ94457.1 | fabD | ZOBELLIA_384 | ZOBELLIA_2406 | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | Malonyl CoA-acyl carrier protein transacylase is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein; High confidence in function and specificity. | 0.999 |
| CAZ94457.1 | lipA | ZOBELLIA_384 | ZOBELLIA_4475 | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity. | 0.871 |
| CAZ94457.1 | qorA1 | ZOBELLIA_384 | ZOBELLIA_4480 | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity. | 0.684 |
| CAZ98612.1 | CAZ98616.1 | ZOBELLIA_4477 | ZOBELLIA_4481 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | 0.567 |
| CAZ98612.1 | CAZ98617.1 | ZOBELLIA_4477 | ZOBELLIA_4482 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Putative protein. | 0.503 |
| CAZ98612.1 | CAZ98618.1 | ZOBELLIA_4477 | ZOBELLIA_4483 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Members of this family are integral membrane proteins that includes the antibiotic resistance protein MarC. These proteins may be transporters; Belongs to the marC (UPF0056) family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | 0.474 |
| CAZ98612.1 | alsD | ZOBELLIA_4477 | ZOBELLIA_4478 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Alpha-acetolactate decarboxylase converts acetolactate into acetoin, which can be secreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in cytoplasmic and/or the outer membrane; High confidence in function and specificity. | 0.673 |
| CAZ98612.1 | lipA | ZOBELLIA_4477 | ZOBELLIA_4475 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity. | 0.668 |
| CAZ98612.1 | pcaC | ZOBELLIA_4477 | ZOBELLIA_4479 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | Modular protein displaying a N-terminal 4-carboxymuconolactone decarboxylase (CMD) domain and a C-terminal conserved domain of unknown function. CMD is involved in protocatechuate catabolism. It converts the 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 4,5-dihydro-5-oxofuran-2-acetate; Localized in the cytoplasm:; High confidence in function and specificity. | 0.933 |
| CAZ98612.1 | qorA1 | ZOBELLIA_4477 | ZOBELLIA_4480 | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity. | 0.625 |
| CAZ98616.1 | CAZ94457.1 | ZOBELLIA_4481 | ZOBELLIA_384 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear. | 0.548 |
| CAZ98616.1 | CAZ98612.1 | ZOBELLIA_4481 | ZOBELLIA_4477 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Antibiotic biosynthesis monooxygenase family protein; Protein containing two consecutive domains Localized in the cytoplasm; Family membership. | 0.567 |
| CAZ98616.1 | CAZ98617.1 | ZOBELLIA_4481 | ZOBELLIA_4482 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Putative protein. | 0.678 |
| CAZ98616.1 | CAZ98618.1 | ZOBELLIA_4481 | ZOBELLIA_4483 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Members of this family are integral membrane proteins that includes the antibiotic resistance protein MarC. These proteins may be transporters; Belongs to the marC (UPF0056) family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | 0.635 |
| CAZ98616.1 | alsD | ZOBELLIA_4481 | ZOBELLIA_4478 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Alpha-acetolactate decarboxylase converts acetolactate into acetoin, which can be secreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in cytoplasmic and/or the outer membrane; High confidence in function and specificity. | 0.671 |
| CAZ98616.1 | lipA | ZOBELLIA_4481 | ZOBELLIA_4475 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity. | 0.506 |
| CAZ98616.1 | pcaC | ZOBELLIA_4481 | ZOBELLIA_4479 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | Modular protein displaying a N-terminal 4-carboxymuconolactone decarboxylase (CMD) domain and a C-terminal conserved domain of unknown function. CMD is involved in protocatechuate catabolism. It converts the 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 4,5-dihydro-5-oxofuran-2-acetate; Localized in the cytoplasm:; High confidence in function and specificity. | 0.743 |
| CAZ98616.1 | qorA1 | ZOBELLIA_4481 | ZOBELLIA_4480 | Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership. | The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity. | 0.748 |