STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ98651.1The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule. Belongs to Gcn5 or GNAT actyltransferase family. Localized in the cytoplasm; Specificity unclear. (161 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.777
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
     
 0.774
hisC
The histidinol-phosphate aminotransferase catalyses the transfer of an amino group from 3-(imidazol-4-yl)-2-oxopropyl phosphate to glutamic acid to form histidinol phosphate and 2-oxoglutarate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. Localized in the cytoplasm; High confidence in function and specificity.
       0.773
hisB
Histidine biosynthesis bifunctional protein HisB; HisB is a bifunctional enzyme containing a N-terminal histidinol-phosphatase (HP) domain and a C-terminal imidazoleglycerol-phosphate dehydratase (IGPD) domain, catalyzing the eighth and sixth steps of L-histidine biosynthetic pathway, respectively. HP catalyzes the dephosphorylation of L-histidinol phosphate. HP forms a homodimer in solution. The active site contains two metal binding sites. IGPD catalyzes the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O. IGPD is a metalloenz [...]
  
    0.737
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.538
CAZ98653.1
Putative protein.
       0.532
CAZ98635.1
Putative membrane lipoprotein; Lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Hypothetical protein.
  
     0.526
CAZ94743.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.504
CAZ97144.1
Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership.
  
    0.486
CAZ94922.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-105) and the Plug module acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Specificity unclear.
  
     0.479
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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