STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CAZ98775.1NmrA family oxidoreductase; Conserved protein belonging to the NmrA-type oxidoreductase family, but its exact function is unknown. NmrA is a negative transcriptional regulator involved in the control of nitrogen metabolite repression in various fungi. Its crystal structure has revealed an unexpected similarity to the short-chain dehydrogenase/reductase (SDR) family. NAD binds to NmrA in vitro. Localized in the cytoplasm; Family membership. (282 aa)    
Predicted Functional Partners:
ytfG
YtfG belongs to the NmrA-type oxidoreductase family, but its exact function is unknown; Localized in the cytoplasm; Family membership.
  
  
 
0.919
wrbA
NAD(P)H dehydrogenase [quinone]; The enzyme catalyse the NAD(P)H-dependent two-electron reductions of quinones; It apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons to protect cells against damage by free radicals and reactive oxygen species; It has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone; Uses a FAD cofactor; Localized in the cytoplasm; High confidence in function and specificity.
  
 
  0.903
menG/ubiE
Menaquinone/ubiquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
    
  0.901
ggcX
Vitamin K-dependent gamma-glutamyl carboxylase is involved in the Vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues in various proteins. It converts glutamate residues to gamma-carboxyglutamate; Contains six transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
  0.900
fdx
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. It binds two 4Fe-4S clusters; Localized in the cytoplasm; Function unclear.
   
 0.875
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
  
 0.787
CAZ96942.1
Rieske [2Fe-2S] iron-sulfur protein; Protein that contains an unknown function N-terminal domain and a C-terminal Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines; Prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear.
  
 
 0.728
CAZ98776.1
Putative protein.
       0.727
sdhB
Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhB is the iron-sulfur subunit. Localized in the cytoplasm; High confidence in function and specificity.
   
 
 0.520
crtB
The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.514
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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