STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ98781.1Conserved hypothetical protein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Lcocalized in the outer membrane. (512 aa)    
Predicted Functional Partners:
ccpA3
The Di-heme cytochrome c peroxidase reduces hydrogen peroxide to water using c-type heme as an oxidizable substrate. However, since it possesses two, instead of one, heme prosthetic groups, CcpA reduce hydrogen peroxide without the need to generate semi-stable free radicals; CcpA is structured into two domains, each containing one c-type heme group, with a calcium-binding site at the domain interface; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity.
 
     0.900
phoB
Alkaline phosphatase; Modular protein that consists of a N-terminal conserved domain of unknown function (240 residues) and a C-terminal Alkaline phosphatase domain; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Specificity unclear.
  
  
 0.475
phoA
Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; High confidence in function and specificity.
  
  
 0.475
CAZ97762.1
Conserved hypothetical protein; This protein displays distant similarity with glycoside hydrolases of the family 74 (GH74). These proteins consist of a tandem repeat of two similar domains, which are both folded into seven-bladed beta- propeller structures. But the two conserved catalytic aspartatic residues are substituted here by two asparagine residues. Features a signal peptide cleaved between the residues 19 and 20.
  
     0.446
gfoA
Glucose-fructose oxidoreductase; To protect the bacterium against osmotic shock, the periplasmic glucose-fructose oxidoreductase produces the compatible, solute sorbitol by reduction of fructose, coupled with the oxidation of glucose to gluconolactone. GfoA formes a homodimer and each subunit contains tightly associated NADP which is not released during the catalytic cycle. It belongs to the GFO/IDH/MOCA family and adopts a Rossmann fold. Features an uncleaved signal peptide. Localized in the periplasm; High confidence in function and specificity.
       0.419
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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