STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fucP2L-fucose-proton symporter; FucP mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose. Features twelve transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity. (447 aa)    
Predicted Functional Partners:
CAZ98821.1
Conserved hypothetical protein; Protein belonging to the DUF718 family, which includes the rhamnose mutarotase YiiL from Escherichia coli; Localized in the cytoplasm.
 
  
 0.951
CAZ98819.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership.
 
    0.799
CAZ98818.1
Amidohydrolase 2 family protein; Belongs to the metal-dependent hydrolase superfamily, Amidohydrolase 2 family; Localized in the cytoplasm; Family membership.
 
  
 0.720
uxaB
Altronate oxidoreductase or Tagaturonate reductase catalyzes the NAD-dependent reduction of altronate into tagaturonate; Belongs to the Long-chain mannitol dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity.
       0.460
manA
Belongs to the family 92 of glycoside hydrolases (GH92); Possibly involved in the mannane degradation or putatively involved in the glycoprotein biosynthesis; Signal peptide of lipoprotein cleaved between the residues 22 and 23; Putatively localized in the outer membrane; High confidence in function and specificity.
 
     0.421
uxaA
Altronate hydrolase or Altronic acid hydratase converts the altronic acid to 2-keto-2-deoxygluconate; it is catalytically inactive in the absence of Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of enzyme is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre; Contains an N-terminal SAF domain; Localized in the cytoplasm; High confidence in function and specificity.
       0.413
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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