STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nnrE-2Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] (517 aa)    
Predicted Functional Partners:
CAZ94207.1
Nucleoside diphosphate pyrophosphatase; This family of proteins catalyses the hydrolysis of phosphorus-containing acid anhydrides such as nucleoside diphosphate, for example ADP-mannose and UDP-glucose; Protein that consists of a NUDIX hydrolases (NUcleoside DIphosphate linked to some other moiety X) domain; Localized in the cytoplasm; Family membership.
  
 0.785
CAZ94607.1
NUDIX hydrolase belongs to a family of enzymes hydrolyzing diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). Localized in the cytoplasm; Function unclear.
  
 0.785
CAZ94754.1
NUDIX hydrolase; This conserved protein belongs to the Nudix (NUcleoside DIphosphate linked to some other moiety X) hydrolase family. Its specificity is unclear; Localized in the cytoplasm; Family membership.
  
 0.785
nnrE
Conserved hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
 
 
 0.754
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.739
CAZ98665.1
This protein belongs to the UPF0079 family. This group consists of bacterial proteins, which contain a P-loop. They are probably essential to bacteria as members are found in all genomes so far sequenced and no equivalent genes have been found in the archaea and eukaryotes. These proteins adopt a nucleotide-binding fold with a four-stranded parallel beta-sheet flanked by antiparallel beta-strands on each side. The topology of the beta-sheet is unique among P-loop proteins and has features of different families of enzymes. ADP has been shown to bind to the P-loop in the presence of Mg2+ [...]
  
 
 0.696
CAZ94899.1
Conserved hypothetical protein; Signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane.
  
     0.552
ftsQ
Possible cell division protein ftsQ; This hypothetical protein could be the FtsQ protein involved in septum formation. Could interact with ftsZ, ftsA, and penicillin binding protein 3. The function of FtsQ is unknown; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
  
 0.550
CAZ98279.1
Conserved hypothetical protein. Localized in the cytoplasm.
 
     0.533
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
  
 
 0.520
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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