node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAZ98118.1 | CAZ98888.1 | ZOBELLIA_3981 | ZOBELLIA_4753 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.779 |
CAZ98118.1 | rlmN | ZOBELLIA_3981 | ZOBELLIA_817 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Radical SAM family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.437 |
CAZ98886.1 | CAZ98888.1 | ZOBELLIA_4751 | ZOBELLIA_4753 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.610 |
CAZ98886.1 | CAZ98889.1 | ZOBELLIA_4751 | ZOBELLIA_4754 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | Nuclease; Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear. | 0.481 |
CAZ98886.1 | CAZ98890.1 | ZOBELLIA_4751 | ZOBELLIA_4755 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | Conserved ion channel belonging to the sodium, Potassium, Calcium ion channel family. Its specificity is unknown. Features five transmembrane helices. Localized in the cytoplasmic membrane; Specificity unclear. | 0.490 |
CAZ98886.1 | gntK2 | ZOBELLIA_4751 | ZOBELLIA_4757 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.464 |
CAZ98886.1 | hbdA | ZOBELLIA_4751 | ZOBELLIA_4752 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | The 3-Hydroxybutyryl-CoA dehydrogenase is involved in butyrate/butanol-producing pathway. It converts the (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.852 |
CAZ98886.1 | miaA | ZOBELLIA_4751 | ZOBELLIA_4756 | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.492 |
CAZ98888.1 | CAZ98118.1 | ZOBELLIA_4753 | ZOBELLIA_3981 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.779 |
CAZ98888.1 | CAZ98886.1 | ZOBELLIA_4753 | ZOBELLIA_4751 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | 0.610 |
CAZ98888.1 | CAZ98889.1 | ZOBELLIA_4753 | ZOBELLIA_4754 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Nuclease; Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear. | 0.645 |
CAZ98888.1 | CAZ98890.1 | ZOBELLIA_4753 | ZOBELLIA_4755 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved ion channel belonging to the sodium, Potassium, Calcium ion channel family. Its specificity is unknown. Features five transmembrane helices. Localized in the cytoplasmic membrane; Specificity unclear. | 0.650 |
CAZ98888.1 | gntK2 | ZOBELLIA_4753 | ZOBELLIA_4757 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.620 |
CAZ98888.1 | hbdA | ZOBELLIA_4753 | ZOBELLIA_4752 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | The 3-Hydroxybutyryl-CoA dehydrogenase is involved in butyrate/butanol-producing pathway. It converts the (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.661 |
CAZ98888.1 | hemN-2 | ZOBELLIA_4753 | ZOBELLIA_2274 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.596 |
CAZ98888.1 | miaA | ZOBELLIA_4753 | ZOBELLIA_4756 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.729 |
CAZ98888.1 | proC1 | ZOBELLIA_4753 | ZOBELLIA_2420 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.814 |
CAZ98888.1 | rlmN | ZOBELLIA_4753 | ZOBELLIA_817 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Radical SAM family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.662 |
CAZ98889.1 | CAZ98886.1 | ZOBELLIA_4754 | ZOBELLIA_4751 | Nuclease; Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear. | NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm; Specificity unclear. | 0.481 |
CAZ98889.1 | CAZ98888.1 | ZOBELLIA_4754 | ZOBELLIA_4753 | Nuclease; Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.645 |