STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcbDPterin-4-alpha-carbinolamine dehydratase is involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. It catalyzes the the dehydration of 4a-hydroxytetrahydrobiopterins. Localized in the cytoplasm; High confidence in function and specificity. (95 aa)    
Predicted Functional Partners:
phhA
Phenylalanine 4-monooxygenase, also known as phenylalanine-4-hydroxylase, is involved in L-phenylalanine biodegradation. It catalyzes the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4a-hydroxytetrahydrobiopterin. It binds Fe(2+) ion as a cofactor. PhhA belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Localized in the cytoplasm; High confidence in function and specificity.
  
 0.980
hmgA
Catalytic activity: Homogentisate + O2 = 4-maleylacetoacetate. Tyrosine metabolism and Styrene degradation; High confidence in function and specificity.
  
  
 0.629
CAZ94548.1
RmlD substrate binding domain family protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
       0.591
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
  
 0.540
CAZ94550.1
Conserved protein belonging to the DUF28 family; Localized in the cytoplasm; Family membership.
       0.527
hpdA
4-hydroxyphenylpyruvate dioxygenase is involved in L_phenylalanine degradation. It oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. HpdA forms a homodimer and binds one iron ion by subunit. Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.497
CAZ95716.1
Protein that belongs to the Glyoxalase superfamily protein Localized in the cytoplasm; Family membership.
  
  
 0.497
CAZ95616.1
Conserved hydrolase belonging to the haloacid dehalogenase family, which includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure consists of two domains, a four helix bundle domain and a alpha/beta domain. Localized in the cytoplasm; Family membership.
  
  
 0.410
CAZ94816.1
Conserved hypothetical membrane protein; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
  
 0.410
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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