STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94550.1Conserved protein belonging to the DUF28 family; Localized in the cytoplasm; Family membership. (236 aa)    
Predicted Functional Partners:
aspS
Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
 
  
 0.774
tyrS
Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
 
   0.753
ruvA
Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
   
 0.663
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.597
tsfA
Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.589
CAZ97238.1
Peptidase family M23 mainly contains endopeptidases that hydrolyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis; Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear.
 
   0.581
rpsB
The ribosomal protein S2 is a part of the ribosomal small subunit (30S) that contributes to the structural integrity of the ribosome; Belongs to the ribosomal protein S2p family; Localized in the cytoplasm; High confidence in function and specificity.
 
    0.576
metG
Methionyl-tRNA synthetase, class Ia; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
   0.570
tigA
Trigger factor (TF) is involved in protein export. It acts as an ATP-independent chaperone by binding to nascent polypeptide chains via ribosomal protein L23 (RplE) and maintaining the newly synthesized protein in an open conformation. Trigger Factor also displays a peptidyl-prolyl-cis-trans-isomerase (PPIase) activity in vitro. TF is composed of an N-terminal domain that mediates association with the large ribosomal subunit, a central substrate binding and PPIase domain with homology to FKBP proteins, and a C-terminal domain of unknown function. TF forms homodimer and monomer; Localiz [...]
  
  
 0.548
rpmF
The ribosomal protein L32 is part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L32p family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.541
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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