STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppk1Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (701 aa)    
Predicted Functional Partners:
CAZ94347.1
Conserved phosphatase belonging to the Ppx/GppA family, which includes exopolyphosphate phosphatase (Ppx) and guanosine pentaphosphate phosphatase (GppA). Its exact specificity is unclear; Localized in the cytoplasm; Specificity unclear.
 
  
 0.935
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.925
CAZ94570.1
Conserved protein belonging to the phosphoglycerate mutase family. Its exact function is unclear. Localized in the cytoplasm; Family membership.
 
     0.858
arsC
Arsenate reductase; ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. Glutaredoxin functions as the electron donor for arsenate reduction. ArsC also uses molybdenum as a cofactor. ArsC expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Localized in the cytoplasm; High confidence in function and specificity.
 
      0.812
ppk2
Polyphosphate kinase 2; Ppk2 was first identified in Pseudomonas aeruginosa by Zhang and cowokers (PNAS, 2006). Ppk2 belongs to a polyphosphate kinase family unrelated to that of Ppk1. Pkk2 also distinguished from PPK1 by the following: synthesis of poly P from GTP or ATP, a preference for Mn2+ over Mg2+, and a stimulation by poly P. The reverse reaction, a poly P-driven nucleoside diphosphate kinase synthesis of GTP from GDP, is 75-fold greater than the forward reaction, poly P synthesis from GTP. Localized in the cytoplasm; High confidence in function and specificity.
 
   
 0.795
pdxH1
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.635
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.546
pyrB
Aspartate carbamoyltransferase catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate (). This is the second step in the de novo biosynthesis of pyrimidine nucleotides; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.486
rrnA
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.480
CAZ94574.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.472
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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