STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndhA1NADH dehydrogenases catalyze the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation; Binds 1 FAD noncovalently per subunit; Contains one tranmembrane segment; Belongs to the NADH dehydrogenase family; Localized in the cytoplasmic membrane; High confidence in function and specificity. (441 aa)    
Predicted Functional Partners:
ndhA2
FAD-dependent pyridine nucleotide-disulphide oxidoreductase, membrane; NADH dehydrogenases catalyze the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation; Binds 1 FAD noncovalently per subunit; Contains two tranmembrane segments; Belongs to the NADH dehydrogenase family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
  
 
0.902
udk
Uridine kinase (pyrimidine ribonucleoside kinase) is the rate-limiting enzyme in the pyrimidine salvage pathway. It catalyzes the reactions: ATP + uridine = ADP + UMP and ATP + cytidine = ADP + CMP. It forms a homotetramer and binds a ATP per subunit as cofactor. Localized in the cytoplasm; High confidence in function and specificity.
      0.464
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.430
fkpB
Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilised in the cis conformation in oligopeptides; Localized in the cytoplasm; High confidence in function and specificity.
  
    0.408
CAZ94604.1
Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.407
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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