STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94128.1Conserved hypothetical protein; Localized in the cytoplasm. (301 aa)    
Predicted Functional Partners:
btuC
Part of the ABC transporter complex btuCDF involved in vitamin B12 import. The complex is composed of two ATP-binding proteins (btuD), two transmembrane proteins and a solute-binding protein (btuF); Contains nine transmembrane segments; Belongs to the periplasmic binding-protein-dependent ABC transporter family, FecCD subfamily; Localized in the cytoplasmic membrane; High confidence in function and specificity.
   
 
 0.911
btuD
Vitamin B12 ABC importer, ATPase component; This protein is the nucleotide-binding domain (ABC ATPase) of the ABC transporter complex btuCDF involved in vitamin B12 import. It is responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Belongs to the ABC transporter family, vitamin B12 importer; Localized in the cytoplasmic membrane as a peripheral membrane protein; High confidence in function and specificity.
  
 
 0.888
btuB
Vitamin B12 TonB-dependent receptor; BtuB protein is localized in the outer membrane and involved in the active translocation of vitamin B12 (cobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein tonB; Contains a N-terminal Plug module (46-157) acting as a channel gate. The signal peptide is cleaved between the residues 20 and 21; High confidence in function and specificity.
  
  
 0.708
CAZ97496.1
This conserved protein belongs to the DUF71 family, which is predicted to bind ATP. It features a strongly conserved motif SGGKD at the N terminus. It is a two-domain protein with a N-terminal Rossmann fold domain and a C-terminal alpha/beta domain. Localized in the cytoplasm; Family membership.
 
     0.481
CAZ97415.1
Amidohydrolase family protein; The exact function of this protein is unknown; Belongs to the Amidohydrolase family; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Family membership.
  
     0.462
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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