STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94658.1Gluconolactonases hydrolyze the gluconolactone formed by glucose oxidoreductase. The proximity of the galactonate dehydratase gene dgoD suggests that this lactonase would be specific for D-galactono-1,4-lactone instead of gluconolactone; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm; Specificity unclear. (332 aa)    
Predicted Functional Partners:
CAZ95740.1
Pyrroloquinoline quinone-dependent dehydrogenase; Dehydrogenase with a N-terminal domain that adopts a beta-propeller fold and binds the pyrroloquinoline quinone (PQQ) as prosthetic group. Contains also a C-type cytochrome domain with a heme group covalently bound by thioether bonds to two conserved cysteine residues; Belongs to the Quinoprotein alcohol dehydrogenase family; Putative lipoprotein signal peptide cleaved between the residues 21 and 22; Possibly localized in the outer membrane; Specificity unclear.
  
  
 0.937
CAZ94621.1
Cytochrome c-containing protein; Protein containing a N-terminal beta-propeller fold domain, three central PBS lyase HEAT-like repeats and a C-terminal cytochrome c domain. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Function unclear.
 
  
 0.935
gnlA
Gluconolactonases hydrolyze the gluconolactone, formed either by the glucose oxidoreductase or by the glucose dehydrogenase in aerobic conditions, to gluconate; Contains a putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; High confidence in function and specificity.
  
  
 
0.924
gntK1
Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.905
gntK2
Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.905
gdhA
Glucose dehydrogenase catalyses the oxidation of D-glucose without prior phosphorylation to D-beta-gluconolactone using NAD or NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.902
gntT1
High-affinity gluconate transporter; GntT is part of the gluconate utilization system Gnt-I. It is a permease responsible for high-affinity intake of gluconate; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
 0.679
CAZ96473.1
Fumarylacetoacetate hydrolase (FAH), or fumarylacetoacetase (FAA) is the last enzyme in the tyrosine catabolic pathway, it hydrolyses fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle; Localized in the cytoplasm; High confidence in function and specificity.
 
   
 0.651
gdhB3
Quinoprotein glucose dehydrogenase; Lipoprotein putatively localized in the outer membrane is a soluble glucose dehydrogenase (s-GDH) that oxidizes glucose to gluconolactone using a quinone as cofactor; Signale peptide cleaved between the residues 18 and 19; Family membership.
   
 0.535
gdhB2
Quinoprotein glucose dehydrogenase; The mature protein is a multidomain protein: The first 430 residues would be The signal peptide is cleaved between the residues 26 and 27; Protein probably localized in the outer membrane; Hypothetical protein.
    
 0.515
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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