STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dgoD-3Galactonate dehydratase, involved in the galactose metabolism, converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; These enzymes feature a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplas; High confidence in function and specificity. (385 aa)    
Predicted Functional Partners:
dgoK
2-Dehydro-3-deoxygalactonokinase catalyzes the second step in D-galactonate degradation: ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-D-galactonate 6-phosphate. Localized in the cytoplasm; High confidence in function and specificity.
 
 0.950
CAZ94392.1
Galactonate dehydratase converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.923
dgoD-2
Galactonate dehydratase is involved in the galactose metabolism. It converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 
0.917
gntT1
High-affinity gluconate transporter; GntT is part of the gluconate utilization system Gnt-I. It is a permease responsible for high-affinity intake of gluconate; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
 0.719
CAZ94658.1
Gluconolactonases hydrolyze the gluconolactone formed by glucose oxidoreductase. The proximity of the galactonate dehydratase gene dgoD suggests that this lactonase would be specific for D-galactono-1,4-lactone instead of gluconolactone; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm; Specificity unclear.
     
 0.507
rimO
MiaB-like tRNA modifying protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.439
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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