STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cinAConserved protein belonging to the CinA family. Contains a N-terminal molybdopterin binding domain and a C-terminal Competence-damaged domain. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. Localized in the cytoplasm; Function unclear. (416 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.949
nadC
Quinolinic acid phosphoribosyl transferase (QPRTase or QAPRTase) or nicotinate-nucleotide pyrophosphorylase catalyses the conversion of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP), in the presence of Mg2+, to nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. This enzyme provides the de novo source of NAMN for NAD biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the NadC/ModD family.
    
 0.938
nadR
Nicotinamide-nucleotide adenylyltransferase / Ribosylnicotinamide kinase; Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction [...]
    
 0.935
nutA
5'-Nucleotidase, phosphatase subunit; The 5'-Nucleotidase is involved in the degradation of extracellular 5'-nucleotides into membrane permeable nucleosides. Usually It is composed of a N-terminal phosphatase domain that provides the ligands to the dimetal cluster and a conserved histidine, which together form the catalytic site and of a C-terminal domain involved in the substrate binding; This lipoprotein corresponds only to the phosphatase domain that hydrolyses the phosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules; Binds a chloride ion [...]
  
 
  0.913
surE
Stationary-phase survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.910
CAZ94668.1
Hpt domain protein; The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. The domain consists of six alpha helices containing a four-helix bundle-folding. Localized in the cytoplasm; Family membership.
  
    0.821
CAZ94669.1
Conserved protein belonging to the Fumarylacetoacetate hydrolase family, but its exact function is not known. Fumarylacetoacetate hydrolase is the last enzyme of the tyrosine catabolic pathway. Localized in the cytoplasm; Family membership.
       0.820
CAZ94670.1
This Exonuclease probably exhibits a 3' to 5' deoxyribonuclease activity or a ribonuclease activity; Contains an exonuclease domain; Localized in the cytoplasm; Family membership.
       0.785
rpmB
Ribosomal protein L28 is a part of the large subunit (50S) of the ribosome; RpmB interacts with the proteins RplQ (L17) and RpmF (L32); Belongs to the ribosomal protein L28p family; Localized in the cytoplasm; High confidence in function and specificity.
       0.694
rpmG
Ribosomal protein L33 is one of the proteins from the large ribosomal subunit (50S); L33 has been shown to be on the surface of 50S subunit; Belongs to the ribosomal protein L33p family; Localized in the cytoplasm; High confidence in function and specificity.
       0.688
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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