STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94668.1Hpt domain protein; The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. The domain consists of six alpha helices containing a four-helix bundle-folding. Localized in the cytoplasm; Family membership. (112 aa)    
Predicted Functional Partners:
cinA
Conserved protein belonging to the CinA family. Contains a N-terminal molybdopterin binding domain and a C-terminal Competence-damaged domain. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. Localized in the cytoplasm; Function unclear.
  
    0.821
CAZ94669.1
Conserved protein belonging to the Fumarylacetoacetate hydrolase family, but its exact function is not known. Fumarylacetoacetate hydrolase is the last enzyme of the tyrosine catabolic pathway. Localized in the cytoplasm; Family membership.
       0.811
CAZ94670.1
This Exonuclease probably exhibits a 3' to 5' deoxyribonuclease activity or a ribonuclease activity; Contains an exonuclease domain; Localized in the cytoplasm; Family membership.
  
    0.767
sprE
The SprE protein could be involved in the gliding motility; Contains four tetratrico peptide repeats (TPRs). TPRs mediate proteinprotein interactions. TPR adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. SprE contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear.
  
     0.659
CAZ95583.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
     0.645
CAZ95839.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 23 and 24; localized in the periplasmic space; Conserved hypothetical protein.
  
     0.631
CAZ94583.1
Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.631
CAZ95470.1
Esterase adopting an alpha/beta hydrolase fold. Its exact specificity is unknown; Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Specificity unclear.
  
     0.624
rpmB
Ribosomal protein L28 is a part of the large subunit (50S) of the ribosome; RpmB interacts with the proteins RplQ (L17) and RpmF (L32); Belongs to the ribosomal protein L28p family; Localized in the cytoplasm; High confidence in function and specificity.
       0.622
CAZ95348.1
Conserved hypothetical protein; Protein that consists of a LysE type translocator domain with six transmembrane segments; Probably localized in the cytoplasmic memmbrane.
  
     0.620
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.