STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
btuDVitamin B12 ABC importer, ATPase component; This protein is the nucleotide-binding domain (ABC ATPase) of the ABC transporter complex btuCDF involved in vitamin B12 import. It is responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Belongs to the ABC transporter family, vitamin B12 importer; Localized in the cytoplasmic membrane as a peripheral membrane protein; High confidence in function and specificity. (229 aa)    
Predicted Functional Partners:
btuF
Part of the ABC transporter complex btuCDF involved in vitamin B12 import. Binds cobalamin (vitamin B12) and delivers it to the periplasmic surface of btuC; Contains 1 Fe/B12 periplasmic-binding domain; belong to the TroA superfamily, btuF family; Signal peptide of lipoprotein cleaved between the residues 15 and 16; Periplasmic protein anchored in the cytoplasmic membrane; High confidence in function and specificity.
 
 
 0.980
btuC
Part of the ABC transporter complex btuCDF involved in vitamin B12 import. The complex is composed of two ATP-binding proteins (btuD), two transmembrane proteins and a solute-binding protein (btuF); Contains nine transmembrane segments; Belongs to the periplasmic binding-protein-dependent ABC transporter family, FecCD subfamily; Localized in the cytoplasmic membrane; High confidence in function and specificity.
   
 0.979
CAZ94128.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
 
 0.888
rmuC
RmuC is involved in DNA recombination, but its exact function is unclear. It is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures. Localized in the cytoplasm; Function unclear.
       0.622
CAZ94136.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein.
       0.622
CAZ94137.1
Acyl-CoA thioesterase hydrolyzes fatty acyl-CoA substrates releasing acyl-Coa and fatty acids. Localized in the cytoplasm; Specificity unclear.
       0.606
CAZ94133.1
Conserved protein belonging to the DUF1080 family. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm; Conserved hypothetical protein.
       0.519
idsA
Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...]
  
     0.478
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   
 0.446
CAZ98466.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership.
 
    0.436
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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