| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAZ94691.1 | CAZ94692.1 | ZOBELLIA_620 | ZOBELLIA_621 | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | 0.687 |
| CAZ94691.1 | nucS | ZOBELLIA_620 | ZOBELLIA_618 | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.496 |
| CAZ94691.1 | pbp1B | ZOBELLIA_620 | ZOBELLIA_619 | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | 0.682 |
| CAZ94692.1 | CAZ94691.1 | ZOBELLIA_621 | ZOBELLIA_620 | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | 0.687 |
| CAZ94692.1 | nucS | ZOBELLIA_621 | ZOBELLIA_618 | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.437 |
| CAZ94692.1 | pbp1B | ZOBELLIA_621 | ZOBELLIA_619 | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | 0.591 |
| CAZ96470.1 | nucS | ZOBELLIA_2315 | ZOBELLIA_618 | TonB-dependent Transducer; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (59-110)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (120-194) and the Plug module (212-335); The signal peptide is cleaved between the residue 29 and 30; Family membership. | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.490 |
| CAZ96996.1 | nucS | ZOBELLIA_2849 | ZOBELLIA_618 | TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-92) and the Plug module (109-232) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership. | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.468 |
| CAZ97825.1 | nucS | ZOBELLIA_3687 | ZOBELLIA_618 | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.431 |
| nucS | CAZ94691.1 | ZOBELLIA_618 | ZOBELLIA_620 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | 0.496 |
| nucS | CAZ94692.1 | ZOBELLIA_618 | ZOBELLIA_621 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | 0.437 |
| nucS | CAZ96470.1 | ZOBELLIA_618 | ZOBELLIA_2315 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | TonB-dependent Transducer; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (59-110)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (120-194) and the Plug module (212-335); The signal peptide is cleaved between the residue 29 and 30; Family membership. | 0.490 |
| nucS | CAZ96996.1 | ZOBELLIA_618 | ZOBELLIA_2849 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-92) and the Plug module (109-232) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership. | 0.468 |
| nucS | CAZ97825.1 | ZOBELLIA_618 | ZOBELLIA_3687 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | Conserved hypothetical membrane protein; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein. | 0.431 |
| nucS | pbp1B | ZOBELLIA_618 | ZOBELLIA_619 | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | 0.543 |
| pbp1B | CAZ94691.1 | ZOBELLIA_619 | ZOBELLIA_620 | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership. | 0.682 |
| pbp1B | CAZ94692.1 | ZOBELLIA_619 | ZOBELLIA_621 | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership. | 0.591 |
| pbp1B | nucS | ZOBELLIA_619 | ZOBELLIA_618 | Penicillin-binding protein 1B, family GT51; Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...] | Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity. | 0.543 |
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