STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)    
Predicted Functional Partners:
rpeA
Ribulose-phosphate 3-epimerase converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Pentose phosphate pathway; Adopts a a TIM barrel fold; Localized in the cytoplasm; High confidence in function and specificity.
  
 0.952
gndA
6-Phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 
 0.932
prsA
Ribose-phosphate pyrophosphokinase converts the D-ribose 5-phosphate to 5-phospho-alpha-D-ribose 1-diphosphate in the Pentose phosphate pathway. Utilized by both the de novo and the salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.930
rpiB
Ribose 5-phosphate isomerase B catalyses the conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.925
hxlA
3-Hexulose-6-phosphate synthase catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxification system. Localized in the cytoplasm; High confidence in function and specificity.
    
 0.921
pgcA
Phosphoglucomutase catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. It participates in both the breakdown and synthesis of glucose. Binds one magnesium as cofactor. Localized in the cytoplasm; High confidence in function and specificity.
    
 0.914
tktB
Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.911
tktA
Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.911
gntK2
Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.905
kduD2
The 2-keto-3-deoxygluconate oxidoreductase or 2-deoxy-D-gluconate 3-dehydrogenase is involved in the pectin degradation in the pectinolytic microorganisms; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.804
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.