STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
mthKThis channel transports potassium ion in response to intracellular calcium ion binding. Eight RCK domains (regulators of K+ conductance) form a gating ring at the intracellular membrane surface. The gating ring uses the free energy of Ca2+ binding in a simple manner to perform mechanical work to open the pore. This channel is a homotetramer and the monomer subunit features three transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity. (337 aa)    
Predicted Functional Partners:
CAZ94728.1
Conserved hypothetical membrane protein; Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
     
 0.820
CAZ94141.1
Conserved hypothetical protein; Contains one N-terminal transmembrane segment; Probably localized in the cytoplasmic membrane.
 
     0.626
CAZ94729.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.619
trkH
TrkH is a low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity. Features ten transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.604
CAZ98535.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; Conserved hypothetical protein.
 
     0.592
CAZ94725.1
Conserved hypothetical membrane protein; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
     
 0.552
CAZ94726.1
Sodium / alanine symporter; This permease transports alanine in association with sodium ions. It forms a channel through the cytoplasmic membrane, the interior face being hydrophilic to allow the passage of alanine molecules and sodium ions. Features eleven transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.548
CAZ94724.1
Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD. Reoxidation of the flavin involves transfer of electrons to ETF (electron transfering flavoprotein). These enzymes are homodimers containing one molecule of FAD; Localized in the cytoplasm; Specificity unclear.
       0.491
moaE2
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; Hypothetical protein.
   
    0.472
moaE1
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin in the second major step of the molybdenum cofactor biosynthesis. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; High confidence in function and specificity.
   
    0.472
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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