STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddlAD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (326 aa)    
Predicted Functional Partners:
murF1
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.992
murC
UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.986
alrA
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.962
murF2
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase, catalytic domain; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF) is an enzyme involved in the final step of the biosynthesis of peptidoglycan which catalyzes the addition of D-alanyl-D-alanine to the nucleotide precursor UDP-N- acetylmuramoyl-L-alanyl-D-glutamyl-meso-2, 6-diaminoheptanedioate; Belongs to the MurCDEF family; This sequence is the N-terminal catalytic domain of MurF only; Localized in the cytoplasm; High confidence in function and specificity.
 
 0.938
murD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.893
mplA
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase is an enzyme involved in the biosynthesis of peptidoglycan which reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramic acid; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity.
  
 0.890
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
   
 0.864
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.850
ftsQ
Possible cell division protein ftsQ; This hypothetical protein could be the FtsQ protein involved in septum formation. Could interact with ftsZ, ftsA, and penicillin binding protein 3. The function of FtsQ is unknown; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
  
 0.830
ftsW
FtsW is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division; Contains ten transmembrane segments; Belongs to the ftsW/rodA/spoVE family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
  
 0.795
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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