STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CAZ94753.1Metallopeptidase, family M14; Metallocarboxypeptidases remove aminoacid residues from the C-terminal end of proteins. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu; Belongs to the family M14 of peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Specificity unclear. (591 aa)    
Predicted Functional Partners:
CAZ94752.1
Two-component system-Response regulator, receiver domain; The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership.
       0.659
CAZ94751.1
The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains one N-terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership.
       0.658
CAZ94163.1
Protein containing four BNR (bacterial neuraminidase repeat) repeats. These repeats are found in many glycoside hydrolases as well as other extracellular proteins of unknown function. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Family membership.
 
     0.497
dppA1
Dipeptidyl-peptidase IV, family S9; Dipeptidyl-peptidase IV releases an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. Belongs to the family S9 of the serine peptidases. The active site residues are in the order Ser, Asp, His in the sequence. The motif around the active site serine is G W S (Y/F) G G. DppA displays a two domain architecture, with a N-terminal eight-bladed beta-propeller and a C-terminal S9 peptidase domain. Features a signal peptide cleaved between the residues 20 and 21. Localiz [...]
 
     0.489
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.447
CAZ95879.1
Conserved protein distantly related to glycoside hydrolases of the family 74 (GH74). Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space.
 
     0.440
CAZ96979.1
Family M28 contains aminopeptidases and carboxypeptidases with two co-catalytic zinc ions (I and II). Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. The zinc ligands occur in the sequence in the order His (II), Asp (I and II), Glu (I), Asp or Glu (II) and His (I). In addition, two other residues, an Asp and a Glu, are believed to be important for catalysis. Four of these residues occur in the motifs His-Xaa-Asp and Glu-Glu. Features a signal peptide cleaved between the residues 20 and 21. Loc [...]
  
     0.428
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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