STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (227 aa)    
Predicted Functional Partners:
pssA
Phosphatidylserine synthase; This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis; Signal peptide cleaved between the residues 24 and 25, Contains six transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.984
pldA
The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels. The active site His and Ser residues are located at the exterior of the beta-barrel, at the outer leaflet side of the membrane; Localized in the outer membrane; High confidence in function and specificity.
     
  0.900
cdsA
Phosphatidate cytidylyltransferase is essential for phospholipid biosynthesis. It catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate: CDP-diacylglycerol is an important branch point intermediate in both prokaryotic and eukaryotic organisms. Features seven transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity; Belongs to the CDS family.
     
 0.865
CAZ94760.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.820
CAZ94763.1
Acyl-CoA binding protein (ACBP) is a small (~10 kDa) protein that binds medium- and long-chain acyl-CoA esters with high affinity, and may act as an intra- cellular carrier of acyl-CoA esters. It is a mainly-alpha protein, consisting of 5 short alpha-helices and 3 connecting beta-strands. Localized in the cytoplasm; Family membership.
       0.820
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 0.726
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.690
rsfS
Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.687
CAZ94757.1
Biotin-[acetyl-CoA-carboxylase]ligase is responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. These enzymes usually transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Localized in the cytoplasm; High confidence in function and specificity.
 
     0.549
CAZ94945.1
ABC transporter, permease component; ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Probably, this protein is the membrane component of an ABC importer; Contains a DUF140 domain and five transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
  
     0.478
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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