STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdmCMdmC is a 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics; Localized in the cytoplasm; High confidence in function and specificity. (213 aa)    
Predicted Functional Partners:
CAZ95856.1
Conserved hypothetical protein; Hypothetical sulfurtransferase that contains one rhodanese domain, Belongs to the UPF0176 family; localized in the cytoplasm.
    
 0.898
CAZ94352.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership.
 
  
 
 0.884
kduD2
The 2-keto-3-deoxygluconate oxidoreductase or 2-deoxy-D-gluconate 3-dehydrogenase is involved in the pectin degradation in the pectinolytic microorganisms; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 
 0.884
CAZ98560.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Specificity unclear.
 
  
 
 0.872
kduD1
2-deoxy-D-gluconate-3-dehydrogenase; Enzyme that belongs to the Pentose and glucuronate interconversions pathway; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 
 0.864
CAZ97610.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership.
 
  
 
 0.844
fabG1
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 
 0.802
idnO3
Gluconate-5-dehydrogenase; Also called 5-keto-D-gluconate 5-reductase; Catalyzes the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 
 0.796
idnO2
Gluconate-5-dehydrogenase; Also called 5-keto-D-gluconate 5-reductase. Catalyzes the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 
 0.778
CAZ96765.1
Acetoin(diacetyl) reductase; The enzymes of this family are very similar and display high sequence identities, the substrate specificity is difficult to determine; A match to Glucose/ribitol dehydrogenase subfamily indicates that the protein is not an alcohol dehydrogenase, but another type of dehydrogenase or reductase; Possible signal peptide cleaved between the residues 20 and 21; Putatively localized in the periplasmic space; Family membership.
 
  
 
 0.660
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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