STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
tatA-2Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (112 aa)    
Predicted Functional Partners:
tatA
Sec-independent protein translocase TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
  
  0.958
tatC
Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
 0.934
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.896
sepP1
Undecaprenyl-diphosphatase catalyzes the hydrolysis of dolichol pyrophosphate, likely in connection with glycosylation reactions of membrane. Features five transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.796
CAZ94793.1
Aminopeptidase, family M1; Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal p [...]
       0.580
hisIE
Histidine biosynthesis bifunctional protein HisIE; HisIE is a bifunctional enzyme containing a N-terminal phosphoribosyl-AMP cyclohydrolase (PRA-CH) domain and a C-terminal phosphoribosyl-ATP pyrophosphatase (PRA-PH) domain, catalyzing the third and second steps of the L-histidine biosynthetic pathway, respectively. PRA-CH catalyzes the reaction: 1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide. It requires Zn ions for activity. PRA-PH catalyzes the reaction: 1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)- [...]
  
    0.550
CAZ94794.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein.
     
 0.524
hmoA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; Contains 4 4Fe-4S type ferredoxin domains and a putatif Twin-arginine translocation pathway signal; Localized in the cytoplasmic membrane; Family membership.
 
 
 0.517
clpS
ClpS is involved in the modulation of the specificity of the clpAP-mediated ATP-dependent protein degradation. It binds to the N-terminal domain of the chaperone ClpA. Localized in the cytoplasm; High confidence in function and specificity.
  
     0.477
secD
Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.430
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.