STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmI2,3-Bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa)    
Predicted Functional Partners:
enoA
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.980
pgkA
Phosphoglycerate kinase transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate in the seventh step of the glycolysis Embden-Meyerhof pathway). PgkA exists as a monomer containing two nearly equal-sized domains that correspond to the N- and C-termini of the protein. 3-phosphoglycerate binds to the N-terminal, while the nucleotide substrates, MgATP or MgADP, bind to the C-terminal domain of the enzyme; Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.979
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.934
serB/serA1
Phosphoserine phosphatase / D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.931
glxK
Glycerate kinase; Enzyme involved in glycine, serine and threonine metabolism, Glycerolipid metabolism and Glyoxylate and dicarboxylate metabolism; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the glycerate kinase type-1 family.
     
 0.908
gapN
The NADP-dependent glyceraldehyde-3-phosphate dehydrogenase is important as a means of generating NADPH for biosynthetic reactions. It converts the D-glyceraldehyde 3-phosphate to 3-phospho-D-glycerate; Forms a homotetramer and binds a NADP+ per subunit as cofactors; Localized in the cytoplasm; High confidence in function and specificity.
   
 0.906
CAZ96283.1
NAD-dependent 2-hydroxyacid dehydrogenase which seems to be specific for the D-isomer of their substrate; Contains a NAD-binding domain; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; Specificity unclear.
    
 0.903
serA2
D-3-phosphoglycerate dehydrogenase; SerA catalyzes the conversion of 3-phosphoglycerate to 3-phosphonooxypyruvate, which is the first step of the serine biosynthesis pathway. SerA2 is composed of a substrate-binding domain (D-isomer specific 2-hydroxyacid dehydrogenase family) and a NAD-binding domain (Rossman fold). Localized in the cytoplasm; High confidence in function and specificity.
    
 0.903
pgiA
Glucose-6-phosphate isomerase is a dimeric enzyme that catalyses the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate in the second step of glycolysis (Embden-Meyerhof pathway) and in oxydative phase of pentose phosphate pathway. PgiA also is involved in the gluconeogenesis and in Pentose phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the GPI family.
  
 
 0.860
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
   
 
 0.843
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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