STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
des6-1Linoleoyl-CoA desaturase, also known as delta 6-desaturase, is responsible for the conversion of linoleic acid (18:2) to gamma-linolenic acid (18:3 gamma). It uses iron ion as a cofactor. Features five transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity. (367 aa)    
Predicted Functional Partners:
des6-2
Linoleoyl-CoA desaturase, also known as delta 6-desaturase, is responsible for the conversion of linoleic acid (18:2) to gamma-linolenic acid (18:3 gamma). It uses iron ion as a cofactor. Features five transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
  
 
0.906
pldA
The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels. The active site His and Ser residues are located at the exterior of the beta-barrel, at the outer leaflet side of the membrane; Localized in the outer membrane; High confidence in function and specificity.
     
  0.900
aatA-2
Aspartate aminotransferase or Transaminase A or Glutamic-aspartic transaminase or Glutamic-oxaloacetic transaminase converts the L-aspartic acid and the 2-oxoglutarate into L-glutamate and oxaloacetate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity.
       0.625
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.584
CAZ95203.1
Conserved hypothetical membrane protein; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.500
CAZ98686.1
Phospholipase, Patatin family; This protein belongs to a phospholipase family including the Patatin, a lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids. Localized in the cytoplasm; Specificity unclear.
  
     0.475
paaE
Phenylacetic acid degradation NADH oxidoreductase; The protein PaaE is involved in the phenylacetic acid aerobic catabolism. It is likely part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation. It is activated by cAMP receptor protein (CRP) and the integration host factor (IHF). Contains a N-terminal FAD-binding domain, a central feredoxin-like NAD-binding domain and a C-terminal 2Fe-2S iron-sulfur cluster binding domain; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.438
CAZ94763.1
Acyl-CoA binding protein (ACBP) is a small (~10 kDa) protein that binds medium- and long-chain acyl-CoA esters with high affinity, and may act as an intra- cellular carrier of acyl-CoA esters. It is a mainly-alpha protein, consisting of 5 short alpha-helices and 3 connecting beta-strands. Localized in the cytoplasm; Family membership.
  
   
 0.424
CAZ95201.1
Protein receptor with a serine/threonine-protein kinase activity and containing seven leucine-rich repeats that generally folds into an arc or horseshoe shape; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Specificity unclear.
  
     0.409
CAZ98235.1
Conserved membrane protein; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.400
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.