STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkATrkA is part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH. Localized in the cytoplasm; High confidence in function and specificity. (449 aa)    
Predicted Functional Partners:
trkH
TrkH is a low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity. Features ten transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
 
 0.974
menG/ubiE
Menaquinone/ubiquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
       0.536
moaE2
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; Hypothetical protein.
   
    0.472
moaE1
Molybdopterin synthase, large subunit; Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin in the second major step of the molybdenum cofactor biosynthesis. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; High confidence in function and specificity.
   
    0.472
hemCD
Porphobilinogen deaminase / Uroporphyrinogen-III synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
    0.454
porT
PorT is essential for the transport of some proteins across the outer membrane from the periplasm to the cell surface; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity.
       0.431
hemD
Uroporphyrinogen-III synthase is the fourth enzyme in the heme biosynthesis pathway. It catalyzes the reaction: hydroxymethylbilane = uroporphyrinogen III + H2O. Localized in the cytoplasm; High confidence in function and specificity.
  
    0.408
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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